:root{--navy:#092e58;--ink:#18334d;--muted:#586a7b;--blue:#1681aa;--purple:#78558e;--line:#d8e1e8;--pale:#f1f5f8;--white:#fff;font-family:Arial,Helvetica,sans-serif;color:var(--ink);background:var(--white);font-synthesis:none}
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@media(min-width:1450px){.home-intro{padding-block:85px 90px}}@media(max-width:1150px){.header-inner{gap:25px}.brand,.brand img{width:180px;flex-basis:180px}.site-header nav{gap:16px}.site-header nav a{font-size:12px}.site-header nav .members-link{padding-left:14px}.home-intro{gap:35px}.calculator-layout{gap:38px}.contact-layout{gap:50px}}
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@media(max-width:680px){.wrap{width:calc(100% - 40px)}.header-inner{width:calc(100% - 40px);padding-block:15px 8px}.brand,.brand img{width:173px}.site-header nav{gap:0 17px;justify-content:flex-start}.site-header nav a{padding-block:8px;font-size:12px}.site-header nav .members-link{border-left:0;padding-left:0}.home-intro{grid-template-columns:1fr;padding-block:39px 42px;gap:30px}.home-intro h1{font-size:42px;letter-spacing:-1.5px}.eyebrow{font-size:10px;letter-spacing:1.4px}.home-intro .lead{font-size:18px}.home-emblem{display:none}.actions{gap:21px}.rationale{grid-template-columns:1fr;gap:10px;padding-block:35px}.rationale .section-label{margin-bottom:10px}.prose{font-size:16px;line-height:1.8}h2{font-size:28px}.study-grid{grid-template-columns:1fr;padding-block:39px;gap:25px}.study-grid h2{font-size:28px}.study-schedule{border-left:0;border-top:1px solid var(--line);padding:28px 0 0}.join-row{display:block;padding-block:38px}.join-row .button{margin-top:15px}.site-footer{display:block;padding:27px 20px;margin-top:35px}.site-footer nav{gap:24px;margin-top:18px}.page-head{padding-block:39px 19px}h1{font-size:39px;letter-spacing:-1.3px}.lead{font-size:18px}.network-stats{gap:20px 15px;grid-template-columns:1fr 1fr;padding-block:22px}.network-stats>div:last-child{grid-column:1/-1}.network-stats strong{font-size:33px}.network-stats>div:last-child strong{font-size:25px}.network-stats span{font-size:11px}.source-note{font-size:11px}.country-section{grid-template-columns:1fr;gap:22px;padding-block:25px}.country-section h2{font-size:23px}.country-section h2 span{display:inline;margin-left:15px}.country-index{gap:7px 19px}.country-index a{font-size:12px}.centre-list span{font-size:15px}.centre-list small{font-size:11px}.team-intro{margin-inline:20px;padding-bottom:13px}.team-group{grid-template-columns:1fr;gap:12px}.team-group>div{grid-template-columns:1fr}.team-group>h2{font-size:24px}.person{margin-bottom:7px;padding-bottom:13px}.person h3{font-size:21px}.patient-layout{display:flex;flex-direction:column;gap:32px}.patient-summary{padding:23px;width:100%}.patient-prose h2{font-size:26px}.patient-prose section{margin-bottom:32px}.contact-layout{grid-template-columns:1fr;gap:25px;margin-bottom:40px}.email-compose{border-left:0;border-top:1px solid var(--line);padding:25px 0 0}.email-address{font-size:18px}.calculator-head{padding-block:28px 12px}.calculator-head h1{font-size:36px}.calculator-head .lead{font-size:14px}.calculator-layout{grid-template-columns:1fr;gap:30px}.clinical-form h2{font-size:21px}.input-grid{gap:0 17px}.input-grid label{font-size:11px}.result-column{border-top:1px solid var(--line);padding-top:22px}.probability-panel{min-height:190px}.login-layout{grid-template-columns:1fr;padding-block:40px;gap:30px}.login-form{padding:25px}.login-layout h1{font-size:38px}.admin-head{padding-block:30px 15px;align-items:flex-start;gap:15px}.admin-head h1{font-size:31px}.admin-head .eyebrow{font-size:9px}.admin-head button{font-size:12px;padding:9px 14px}.section-toolbar{align-items:flex-start;gap:15px}.section-toolbar h2{font-size:22px}.section-toolbar .button{font-size:12px;padding:9px 13px}.admin-countries{grid-template-columns:1fr}.admin-predictions th,.admin-predictions td{white-space:nowrap}.centres-table{min-width:720px}.edit-form{margin-bottom:50px}.narrow{margin-bottom:50px}}
.contact-people{margin:0 0 28px}.contact-people>div{padding:12px 0;border-bottom:1px solid var(--line)}.contact-people dt{font-size:15px;font-weight:500}.contact-people dd,.contact-people a{font-size:14px;overflow-wrap:anywhere}.contact-people dd{margin-top:3px}
meter::-webkit-meter-bar{background:#e6edf2;border:0;border-radius:0}meter::-webkit-meter-optimum-value{background:#258bad}meter::-moz-meter-bar{background:#258bad}
@media(prefers-reduced-motion:reduce){*{scroll-behavior:auto!important}}
.launch-banner{background:var(--pale);border-bottom:1px solid var(--line)}.launch-inner{min-height:125px;display:grid;grid-template-columns:1.05fr 1.55fr auto;align-items:center;gap:48px}.launch-heading .eyebrow{margin-bottom:8px}.launch-heading h2{font-size:24px;margin:0}.launch-dates{display:grid;grid-template-columns:1fr 1fr;gap:34px;margin:0}.launch-dates>div{border-left:1px solid #bacbd7;padding-left:22px}.launch-dates dt{color:var(--navy);font-size:20px;font-weight:500;line-height:1.3}.launch-dates dd{color:var(--muted);font-size:12px;line-height:1.5;margin-top:5px}.launch-actions{display:flex;align-items:center;gap:24px}.launch-actions .button{white-space:nowrap}.launch-actions .text-link{white-space:nowrap}
@media(max-width:930px){.launch-inner{grid-template-columns:1fr 1.5fr;gap:25px 38px;padding-block:24px}.launch-actions{grid-column:1/-1}.launch-heading h2{font-size:22px}}
@media(max-width:680px){.launch-inner{grid-template-columns:1fr;gap:20px;padding-block:26px}.launch-dates{grid-template-columns:1fr 1fr;gap:16px}.launch-dates>div{padding-left:15px}.launch-dates dt{font-size:18px}.launch-actions{grid-column:auto;gap:20px;align-items:flex-start}.launch-actions .button{white-space:normal}.launch-heading h2{font-size:23px}}

/* A single pale-blue pause for practical participation information. */
.patient-participation{padding-block:48px;margin-bottom:48px}.patient-participation .narrow{margin-bottom:0;font-size:17px;line-height:1.85}.patient-participation h2{font-size:29px}.patient-participation a{font-size:14px;font-weight:600}.patient-followup{margin-bottom:65px}
@media(max-width:680px){.patient-participation{padding-block:32px;margin-bottom:32px}.patient-participation .narrow{font-size:16px;line-height:1.8}.patient-participation h2{font-size:26px}.patient-followup{margin-bottom:40px}}

/* Subtle wayfinding accents for the consortium directories. */
.team-group>h2::before{content:"";display:block;width:32px;height:2px;background:#b9d5e2;margin-bottom:16px}
.country-section h2{color:#456e87}

/* Scientific figures share the original consortium palette. */
.network-atlas{margin:38px 0 24px}.atlas-heading{display:flex;align-items:baseline;justify-content:space-between;gap:20px}.atlas-heading h2{font-size:25px}.map-legend{display:flex;gap:18px;flex-wrap:wrap;font-size:11px;color:var(--muted)}.map-legend span{display:flex;align-items:center;gap:7px}.map-legend i{display:inline-block;width:12px;height:9px;background:#6b96b3}.map-legend .city-key{width:9px;height:9px;background:var(--purple);border:2px solid var(--navy);border-radius:50%}.atlas-panels{display:grid;grid-template-columns:1fr;align-items:start}.map-panel h3{font-size:11px;letter-spacing:1px;text-transform:uppercase;color:var(--muted);font-weight:400;margin-bottom:10px}.map-panel+.map-panel{border-left:1px solid var(--line);padding-left:24px}.network-map{width:100%;display:block;overflow:hidden}.map-land{fill:#e0edf4;stroke:white;stroke-width:.6px;vector-effect:non-scaling-stroke}.map-participant{fill:#6b96b3}.map-city{fill:var(--purple);stroke:var(--navy);stroke-width:1.2px;vector-effect:non-scaling-stroke}.network-map a:hover .map-participant,.network-map a:focus .map-participant{fill:#456e87}.network-map a:focus .map-city,.network-map a:hover .map-city{fill:#ac83bf;stroke-width:2px}.network-atlas figcaption{font-size:11px;color:var(--muted);margin-top:18px;max-width:850px}.map-fields{border:0;border-top:1px solid var(--line);padding:22px 0 0;margin:20px 0}.map-fields legend{font-size:17px;padding-right:12px}.coordinate-fields{display:grid;grid-template-columns:1fr 1fr;gap:20px}
.scientific-flow{margin-block:0 65px}.scientific-flow ol{display:grid;grid-template-columns:repeat(3,1fr);gap:55px;padding:0;list-style:none;margin:0}.scientific-flow li{position:relative}.scientific-flow li+li::before{content:"→";position:absolute;left:-38px;top:22px;color:#90aebf;font-size:23px}.scientific-flow svg{width:120px;height:68px;fill:none;stroke:var(--navy);stroke-width:1.7;stroke-linejoin:round;stroke-linecap:round;margin-bottom:20px}.scientific-flow .diagram-blue{fill:#d5e6ef;stroke:#6b96b3}.scientific-flow .diagram-purple{fill:var(--purple);stroke:var(--navy)}.scientific-flow h3{font-size:19px;font-weight:500;margin-bottom:8px}.scientific-flow p{font-size:14px;color:var(--muted);margin:0}
.patient-timeline{list-style:none;display:grid;grid-template-columns:repeat(3,1fr);padding:0;margin:30px 0;gap:0}.patient-timeline li{position:relative;padding:30px 24px 0 0;border-top:2px solid #b9d5e2}.timeline-point{position:absolute;top:-6px;left:0;width:10px;height:10px;border:2px solid var(--navy);background:var(--purple);border-radius:50%}.patient-timeline h3{font-size:18px;font-weight:500;margin-bottom:10px}.patient-timeline p{font-size:14px;line-height:1.6;margin-bottom:0}
@media(max-width:930px){.atlas-heading{display:block}.map-legend{margin-bottom:20px}.atlas-panels{grid-template-columns:1fr}.map-panel+.map-panel{padding-left:18px}.scientific-flow ol{gap:35px}.scientific-flow li+li::before{left:-28px}}
@media(max-width:680px){.atlas-panels{grid-template-columns:1fr;gap:25px}.map-panel+.map-panel{border-left:0;padding:0}.map-panel:last-child .network-map{max-height:290px}.atlas-heading h2{font-size:23px}.scientific-flow{margin-bottom:38px}.scientific-flow ol{grid-template-columns:1fr;gap:30px}.scientific-flow li{padding-left:105px;min-height:75px}.scientific-flow svg{position:absolute;left:0;top:0;width:80px;height:50px;margin:0}.scientific-flow li+li::before{content:"↓";left:33px;top:-31px;font-size:20px}.scientific-flow h3{font-size:18px}.patient-timeline{grid-template-columns:1fr;margin-block:28px}.patient-timeline li{border-top:0;border-left:2px solid #b9d5e2;padding:0 0 28px 25px;margin-left:5px}.patient-timeline li:last-child{padding-bottom:0;border-left-color:transparent}.timeline-point{left:-6px;top:7px}.patient-timeline p{margin-bottom:0}}

.person-with-portrait{display:grid;grid-template-columns:72px minmax(0,1fr);gap:17px;align-items:start}.portrait-frame{width:72px;height:72px;overflow:hidden}.portrait{display:block;width:72px;height:72px;object-fit:cover;object-position:center 25%}.portrait-pensier{transform:scale(1.25);transform-origin:50% 28%;object-position:50% 24%}
.committee-pending{color:var(--muted);font-size:14px;margin:3px 0 28px}
@media(min-width:681px) and (max-width:1100px){.team-group>div{grid-template-columns:1fr}}

/* Public network summary: one consistent country-and-count model. */
.network-stats{grid-template-columns:repeat(3,1fr)}
.network-directory{display:grid;grid-template-columns:1fr 1fr;column-gap:55px;margin:10px 0 65px}
.country-section{display:flex;align-items:baseline;justify-content:space-between;gap:25px;padding:17px 0}
.country-section h2{font-size:18px}
.country-section p{font-size:13px;color:var(--muted);margin:0;white-space:nowrap}
.country-section p strong{color:var(--navy);font-size:17px;font-weight:500}
.map-legend .country-key{width:9px;height:9px;background:var(--purple);border:2px solid var(--navy);border-radius:50%}
.map-country-marker{fill:var(--purple);stroke:var(--navy);stroke-width:1.2px;vector-effect:non-scaling-stroke}
.network-map a:focus .map-country-marker,.network-map a:hover .map-country-marker{fill:#ac83bf;stroke-width:2px}
@media(max-width:680px){.network-stats{grid-template-columns:repeat(3,1fr)}.network-stats>div:last-child{grid-column:auto}.network-stats>div:last-child strong{font-size:33px}.network-directory{grid-template-columns:1fr;column-gap:0;margin-bottom:40px}.country-section{display:flex;gap:18px;padding:14px 0}.country-section h2{font-size:17px}}

/* A compact network invitation for visitors entering through AI-CLARITY. */
.calculator-join-band{margin-bottom:42px}
.calculator-join{display:flex;align-items:center;justify-content:space-between;gap:55px;padding-block:26px}
.calculator-join>div{max-width:780px}
.calculator-join .eyebrow{margin-bottom:8px}
.calculator-join h2{font-size:24px;margin-bottom:7px}
.calculator-join p:last-child{font-size:15px;margin:0}
.calculator-join .button{flex-shrink:0}
@media(max-width:680px){.calculator-join-band{margin-bottom:30px}.calculator-join{display:block;padding-block:25px}.calculator-join h2{font-size:22px}.calculator-join .button{margin-top:19px}.input-grid input,.input-grid select{font-size:16px}}